Methandrostenolone (dianabol) inject
Tekst van de "officiële" bijsluiter.
Active ingredients.
Metandrostenolone (dianabol)
Composition
Every 1ml contains 50mg of methandrostenolone in oil base carrier and Benzyl-alcohol 1,5%.
Mechanism of action and pharmacokinetics
Methandrostenolone, when injected, provides a peak release of the steroid, whitin one day after injection and sustain hormone release for approximately 2-3 days.
This sustain release of the drug is due to the time that needs the hormone to be transferred from the injection site to the bloodstream. Once in the blood,it has a half-life of 4,5 - 6 hours.
This more slow and even release of the drug, is the reason why the injectable form of methandrostenolone is preferable to the oral form.
Methandrostenolone acts similarly to testosterone although it does carry a more favorable balance towards anabolism than andragonism. It is metabolized into methylestradiol by aromatase. This means thatthat without the administration of aromatase inhibitors such as anastrozole or aminoglutethimide, estrogenic effects will appear over time in men. It also has the effect of decreasing the steroid.'s affinity for sex hormone binding globulin (SHBG), a protein that deactivates steroid molecules and prevents them from further reactions with the body. As a result, methandrostenolone is significantly more than an equivalent quantity of testosterone, resulting in rapid growth of muscle tissue.
However, the concomitant elevation in estrogen levels (a result of the aromatization of methandrostenolone) results in significant water retention. Once metabolized, the drug has the effect of of increasing nitrogen uptake by muscles, leading to an increase in the rate of protein synthesis. It als has the secondary effects of stimulating appetite, reducing the amount of fat being deposit in the body, and decreasing the rate of catabolism.
Indications
Methandrostenolone is indicated for increasing very fast the muscular mass and strenght but with high water retention and high estrogenic activity, as well as increasing the metabolic rate, wich means an increase of the fat burning rate.
Since women will suffer virilization effects even at small doses, this drug should not be taken by a female.
Contraindications
Methandrostenolone is contraindicated in men with carcinomas of the breast or with known suspected carcinomas of the prostate or liver/renal disease and in women in general. Also in men with hypersensitivity to the drug or any of its excipients.
Drug interactions
In diabetic patients, the metabolic effects of methandrostenolone may decrease blood glucose and insulin requirements.
Precautions
Methandrostenolone, through its metabolic effects, stimulates the nervous, mental, and physical activities of a patient. Therefore it should be used with caution in the presence of cardiovasculair and renal diseases, especially in the elderly male.
Prolonged administration or excessive dosage may cause inhibition testicular function. As a result, oligospermia may develop, and there may be a decrease in ejaculatory volume.
Anaphylactic reactions, although rare, may occur, and treatment should be readily available.
Hypersensitivity reactions, including rash and dermatitis, have been reported.
Dosage
Methandrostenolone is administered by intramuscular injection.
It must be not given intravenously.
Intramuscular injections should be given deep in the gluteal muscle.
Males: 50 -150 mg/week, given 2-3 times weekly.
Females: N.A.
Storage
Store in a dark, dry place, at room temperature. Do not refrigerate.
Keep out of the reach of children.
This medicine must be given only by medical description.
Tekst van de "officiële" bijsluiter.
Active ingredients.
Metandrostenolone (dianabol)
Composition
Every 1ml contains 50mg of methandrostenolone in oil base carrier and Benzyl-alcohol 1,5%.
Mechanism of action and pharmacokinetics
Methandrostenolone, when injected, provides a peak release of the steroid, whitin one day after injection and sustain hormone release for approximately 2-3 days.
This sustain release of the drug is due to the time that needs the hormone to be transferred from the injection site to the bloodstream. Once in the blood,it has a half-life of 4,5 - 6 hours.
This more slow and even release of the drug, is the reason why the injectable form of methandrostenolone is preferable to the oral form.
Methandrostenolone acts similarly to testosterone although it does carry a more favorable balance towards anabolism than andragonism. It is metabolized into methylestradiol by aromatase. This means thatthat without the administration of aromatase inhibitors such as anastrozole or aminoglutethimide, estrogenic effects will appear over time in men. It also has the effect of decreasing the steroid.'s affinity for sex hormone binding globulin (SHBG), a protein that deactivates steroid molecules and prevents them from further reactions with the body. As a result, methandrostenolone is significantly more than an equivalent quantity of testosterone, resulting in rapid growth of muscle tissue.
However, the concomitant elevation in estrogen levels (a result of the aromatization of methandrostenolone) results in significant water retention. Once metabolized, the drug has the effect of of increasing nitrogen uptake by muscles, leading to an increase in the rate of protein synthesis. It als has the secondary effects of stimulating appetite, reducing the amount of fat being deposit in the body, and decreasing the rate of catabolism.
Indications
Methandrostenolone is indicated for increasing very fast the muscular mass and strenght but with high water retention and high estrogenic activity, as well as increasing the metabolic rate, wich means an increase of the fat burning rate.
Since women will suffer virilization effects even at small doses, this drug should not be taken by a female.
Contraindications
Methandrostenolone is contraindicated in men with carcinomas of the breast or with known suspected carcinomas of the prostate or liver/renal disease and in women in general. Also in men with hypersensitivity to the drug or any of its excipients.
Drug interactions
In diabetic patients, the metabolic effects of methandrostenolone may decrease blood glucose and insulin requirements.
Precautions
Methandrostenolone, through its metabolic effects, stimulates the nervous, mental, and physical activities of a patient. Therefore it should be used with caution in the presence of cardiovasculair and renal diseases, especially in the elderly male.
Prolonged administration or excessive dosage may cause inhibition testicular function. As a result, oligospermia may develop, and there may be a decrease in ejaculatory volume.
Anaphylactic reactions, although rare, may occur, and treatment should be readily available.
Hypersensitivity reactions, including rash and dermatitis, have been reported.
Dosage
Methandrostenolone is administered by intramuscular injection.
It must be not given intravenously.
Intramuscular injections should be given deep in the gluteal muscle.
Males: 50 -150 mg/week, given 2-3 times weekly.
Females: N.A.
Storage
Store in a dark, dry place, at room temperature. Do not refrigerate.
Keep out of the reach of children.
This medicine must be given only by medical description.
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