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Ik wilde even zeggen dat ik die Tritan Shakebekers echt toppertjes vind. Ik heb de groene en roze nu in mijn collectie, maar zou de blauwe graag nog willen hebben. Enig idee wanneer/of die nog op voorraad komt?
De naam Myoblock is dus volledig misleidend in deze? Echt die supplementenindustrie is me toch een partij misleidend bij 90% van de producten in deze categorie
De naam Myoblock is dus volledig misleidend in deze? Echt die supplementenindustrie is me toch een partij misleidend bij 90% van de producten in deze categorie
Deze snap ik even niet. Het gaat hier om de stof: Epicatechin volgens meerdere onderzoeken heeft dit een effect op myostatin. De andere stoffen zijn ter ondersteuning.
Deze snap ik even niet. Het gaat hier om de stof: Epicatechin volgens meerdere onderzoeken heeft dit een effect op myostatin. De andere stoffen zijn ter ondersteuning.
The purpose of the study was to determine if cycling exercise combined with (–)-epicatechin supplementation was more effective at increasing training adaptations than cycling combined with a placebo. Blood and muscle samples were obtained at rest ...
www.ncbi.nlm.nih.gov
"Results indicate that (–)-epicatechin supplementation does not affect myostatin gene expression or anaerobic training adaptations but inhibits aerobic and mitochondrial SDH adaptations to cycle exercise training."
Verder:
Sarcopenia is a notable and debilitating age-associated condition. Flavonoids are known for their healthy effects and limited toxicity. The flavanol (-)-epicatechin (Epi) enhances exercise capacity in mice, and Epi-rich cocoa improves skeletal muscle structure in heart failure patients...
To investigate the effects of resistance training and epicatechin supplementation on muscle strength, follistatin, and myostatin in older adults with sarcopenia, a total of 62 males with sarcopenia (68.63 ± 2.86 years) underwent a supervised 8-week randomized controlled trial. Participants were...
The purpose of the study was to determine if cycling exercise combined with (–)-epicatechin supplementation was more effective at increasing training adaptations than cycling combined with a placebo. Blood and muscle samples were obtained at rest ...
www.ncbi.nlm.nih.gov
"Results indicate that (–)-epicatechin supplementation does not affect myostatin gene expression or anaerobic training adaptations but inhibits aerobic and mitochondrial SDH adaptations to cycle exercise training."
Verder:
Sarcopenia is a notable and debilitating age-associated condition. Flavonoids are known for their healthy effects and limited toxicity. The flavanol (-)-epicatechin (Epi) enhances exercise capacity in mice, and Epi-rich cocoa improves skeletal muscle structure in heart failure patients...
To investigate the effects of resistance training and epicatechin supplementation on muscle strength, follistatin, and myostatin in older adults with sarcopenia, a total of 62 males with sarcopenia (68.63 ± 2.86 years) underwent a supervised 8-week randomized controlled trial. Participants were...
Voordat wij het product uitbrachten waren er meerdere onderzoeken met positieve effecten. Waren ook al USA merken op de markt met deze stof, reviews daarover waren toch positief. Dat is de reden dat wij het ook gebracht hebben.
Voordat wij het product uitbrachten waren er meerdere onderzoeken met positieve effecten. Waren ook al USA merken op de markt met deze stof, reviews daarover waren toch positief. Dat is de reden dat wij het ook gebracht hebben.
Wees maar niet bang, ik heb het vanmiddag besteld, geprofiteerd van het voordeel.
En van nog wat (m'n favosaus was in de aanbieding o.a.), dus ik zat al gelijk weer boven de € 100.
A simple and sensitive reversed phase high-performance liquid chromatographic (HPLC) method has been developed for the determination of catechin and epicatechin in cocoa powder and chocolates. The separation was achieved on a reversed phase C 18 column (TARGA) 5 μm by gradient elution with a...
The antioxidant polyphenols in cacao liquor, a major ingredient of chocolate and cocoa, have been characterized as flavan-3-ols and proanthocyanidin oligomers. In this study, various cacao products were analyzed by normal-phase HPLC, and the profiles and quantities of the polyphenols present...
In the United States, commercially available foods, including cocoa and chocolate, are being marketed with statements referring to the level of antioxidant activity and polyphenols. For cocoa-containing foods, there has been no comprehensive survey of the content of these and other chemistries...
A recent study has revived the supplement market’s interest in a compound called (-)-epicatechin, a molecule found in chocolate. This molecule is claimed to be a myostatin inhibitor. Myostatin deficiencies are well known for their biggest side effect: greatly increased muscle mass without the major side-effects associated with anabolic steroids. Hindering myostatin’s actions would be able to replicate this effect.
Myostatin is a myokine, a kind of regulating molecule released by muscles. The ‘opposite’ of myostatin is a myokine called follistatin. Unlike myostatin, which suppresses muscular growth, follistatin indirectly promotes muscle growth because it hinders myostatin signalling.
While there are a few supplements that are known to interact with myostatin signaling (like sulforaphane), none had been tested in the context of human supplementation, until now.
This recent study examined the effects of (-)-epicatechin when supplemented by people.[1] Already, new supplements are popping up on the shelves, containing (-)-epicatechin and claiming to be myostatin inhibitors.
Myostatin and follistatin both have potential to alter muscle growth rates, but supplements and foods affecting these molecules have limited evidence in humans.
Should you supplement (-)-epicatechin or eat more chocolate to build muscle? Let’s dissect the study and find out.
This was a proof of concept study in three parts. A proof of concept study is designed to test whether a compound will have the effect researchers hypothesized, as well as determine if further studies are appropriate.
The first part of the study was done in vitro, meaning outside the body in a test tube or petri dish. Scientists assessed muscle cells taken from people of different ages. When people age, their muscles tend to have higher myostatin levels and lower follistatin levels. The in vitro part of the study confirmed this relationship.
The second part of the study was the mouse study. After measuring the myostatin and follistatin levels of old and young mice to confirm the age-related difference, researchers gave the rats 1 mg (-)-epicatechin per kg of body weight, twice a day. Over two weeks, young mice experienced a 15% decrease in myostatin with no change to follistatin. Older mice, meanwhile, experienced an 18% reduction in myostatin and a 30% increase in follistatin.
Two weeks is not enough time to notice any changes in muscle tissue mass, so researchers did not measure it.
In the third part of the study, six middle-aged people supplemented 1 mg of (-)-epicatechin per kg of body weight, twice a day. This translated to about 75 mg of (-)-epicatechin, twice a day, for a total daily dose of 150 mg.
The published study reports that the follistatin to myostatin ratio of the six middle-aged subjects increased +49.2% (follistatin)/ -16.6% (myostatin), which suggests an increase in follistatin levels and a decrease in myostatin levels. However, the exact changes in myostatin and follistatin levels were not reported.
Though a minor (7%) increase in hand grip strength was observed, muscle tissue mass was not measured, and there was no placebo group for comparison.
This study fulfilled the goals of a proof of concept study, because it provides evidence to suggest a possible relationship between (-)-epicatechin, follistatin, and myostatin levels, which can be investigated in future studies.
A recent study is the first to show that supplemental (-)-epicatechin increases the follistatin to myostatin ratio in humans.
The biggest difference between this study and the new myostatin supplements are the doses. The study used a 150 mg daily dose, while the supplements range from 250 - 500 mg (-)-epicatechin per dose, for a total daily dose of 500 mg - 1,000 mg.
Unfortunately, chocolate probably isn't a reliable way to obtain this much (-)-epicatechin because the amount varies considerably between brands and even with the most (-)-epicatechin-rich products, it would require a lot of chocolate. To get 150 mg of (-)-epicatechin per day you would need to eat about 120 g of the most (-)-epicatechin-rich chocolate bars, and more than 200 g of most dark chocolate.[2][3][4][5] This would contain a considerable amount of calories. Many dark chocolate products have much less, and the percentage of cocoa can't fully explain the differences, so you'd have to have detailed information on the products you use.
For pure cocoa powder, you'd need roughly 100 g. Milk and white chocolate have a much lower cocoa content and subsequently, contain little to no (-)-epicatechin.
It's possible that the other compounds in chocolate could confer similar benefits and less chocolate would be needed for an effect, but this could only be shown through studies using chocolate specifically. For now, supplementation is the best bet to ensure you get the studied dose.
It’s difficult to obtain the studied levels of (-)-epicatechin by consuming dark chocolate or even pure cocoa powder. Supplementation is the surest bet to get an effective amount.
Keep in mind, this study had a very small sample size, just six people, and there was no placebo control. Furthermore, only the ratio of myostatin and follistatin changes were published, not the actual numbers. This study does not provide evidence to recommend (-)-epicatechin as a muscle growth agent, but it does lay the groundwork for future research and suggests (-)-epicatechin is a promising muscle growth supplement.
Since (-)-epicatechin provides other health benefits and is very safe, it is possible to test this potential muscle growth agent for yourself by eating dark chocolate twice a day.
In the future, (-)-epicatechin may be a novel and exciting muscle growth enhancing compound, but there is not enough evidence to recommended it as a dedicated dietary supplement today.
Due to the preliminary nature of studies, there is not currently enough evidence to support (-)-epicatechin for muscle growth. However, dark chocolate is safe and provides other health benefits, so consuming it regularly may not be a bad idea.
Ik wilde even zeggen dat ik die Tritan Shakebekers echt toppertjes vind. Ik heb de groene en roze nu in mijn collectie, maar zou de blauwe graag nog willen hebben. Enig idee wanneer/of die nog op voorraad komt?
Wees maar niet bang, ik heb het vanmiddag besteld, geprofiteerd van het voordeel.
En van nog wat (m'n favosaus was in de aanbieding o.a.), dus ik zat al gelijk weer boven de € 100.
Even vraagje, heb o.a. twee meals gekocht om te proberen maar zag geen bewaringsadvies op de verpakking.
Het gaat om Penne Bolognese en Chicken & Rice in creamy sauce.
Even vraagje, heb o.a. twee meals gekocht om te proberen maar zag geen bewaringsadvies op de verpakking.
Het gaat om Penne Bolognese en Chicken & Rice in creamy sauce.
Hi even een vraagje.
Ik heb nog een zak van deze staan.
De voedingswaade snap ik alleen niet.
Er staat op dat het product 84 gr eiwit bevat en 381 kcal. Het bevat geen vet en kh.
Als ik het bereken kom ik met 4*84 uit op 336 kcal.
Ik zie de zakken niet meer op jullie site maar nu wel potten met de naturel smaak. Alleen staat daar exact dezelfde hoeveelheid eiwitten op (en geen KG en vet) maar deze is 341 kcal. Wat is het verschil met de zakken? of staat het op de zakken fout?
Heb onlangs de XXL Soundwave besteld, superchille koptelefoon.
Alleen bluetooth werkt alleen als ik mijn telefoon 10 cm van de koptelefoon af hou. Als ik hem in mijn broekzak doe tijdens het sporten heb ik geen verbinding meer, nog tips ?