One novel use for Winstrol in any cycle (perhaps even bulking) would be to use it at a very limited dose, in order to lower SHBG. (2) One of the properties of Winstrol is it’s profound ability to lower SHBG much more than other steroids. A dose of .2mg/kg lowered SHBG significantly, which would in turn, raise the amoung of free testosterone circulating in the body. As with 99% of steroids, however,
it’s important to note that suppression of your natural hormonal levels will occur (though perhaps not to the extent that it will with many other steroids).(10) As with running virtually any compound, testosterone supplementation (i.e. running test in a cycle containing Winstrol) is warranted to avoid possible coïtusual dysfunction.
Although the anabolic ratio of this product is very high as compared to its androgenic actions, not many people report huge weight gains off of Stanozolol. Also, interestingly, it has a relatively weak AR binding ability (7), which is quite unusual for a “cutting” steroid. Many of the effects of this drug, as relates to building muscle, are probably from its very high protein synthesizing ability (6) (8). In addition, since this compound is derived from DHT, it tends to promote a very nice, “quality” look to the user’s muscles, with little or no water retention. Winstrol does not aromatize at any rate and has even been speculated to have anti-progestenic properties (in at least some cases, where it may “block” that receptor) (9). If one were to run ancillary compounds with Stanozolol, perhaps Tamoxifen would be appropriate for it’s beneficial effects on blood lipids, but an anti-estrogen (in it’s classic sense) would be unwarranted; proper post cycle therapy is still needed, though.
http://forums.steroid.com/showthread.php?t=199794
References:
1. Trop Doct. 2004 Jul;34(3):149-52.
2. J Clin Endocrinol Metab. 1989 Jun;68(6):1195-200
3. JAMA. 1989 Feb 24;261(8):1165-8.
4. J Steroid Biochem Mol Biol. 2005 Jan;93(1):43-8. Epub 2005 Jan 25.
5. Di Yi Jun Yi Da Xue Xue Bao. 2003 Nov;23(11):1117-20.
6. Can J Vet Res. 2000 Oct;64(4):246-8.
7. Endocrinology. 1984 Jun;114(6):2100-6.
8. J Am Vet Med Assoc. 1997 Sep 15;211(6):719-22
9. Agents Actions. 1994 Mar;41(1-2):37-43.
10. Chemical Muscle Enhancement
11. J Invest Dermatol. 1998 Dec;111(6):1193-7.