Melanotan en bijwerkingen

[2hard2die]

van melanotan.org.

Even een goed stuk om te lezen voor iedereen die melanotan gebruikt,

Ook (of vooral) degene die al langer en of vaker MTII gebruiken...

Bijwerkingen, allergische reacties van melanotan:



I know I have been missing in action for quite awhile, but I have some important information that I wanted to share with you all. People have asked me from time to time if there are any long-term or short-term dangers associated with taking Melanotan. I have always maintained that it is non-toxic to the human body as has been documented in the original Epitan Clincal Phase I/II trials. However, most of these safety trials were performed using the "melanotan one" version of the drug, which is a linear polypeptide and only slightly different from the natural human a-MSH hormone. On the other hand, melanotan II is a more radical departure from the afore-mentioned polypeptide. This polypeptide is cyclic and it is this shape that enables it to bind more tightly to all of the melanocortin receptors than the linear version, which binds best to the melanocortin receptor (MC-1R) found on melanocyte cells.

Because melanotan II is a foreign substance to the body, it invokes an immune system response akin to an allergic reaction. Many of the so-called side-effects you have either heard about or experienced yourself are due to an abundant overdose of melanotan II in your blood. Wheezing, sneezing, congestion, facial flushing, and nausea are all possible symptoms. But your immune system must first be taught to recognize the melanotan II peptide before you might actually experience these side-effects ... which is why first time users usually don't have any adverse reactions. Upon first introduction (or perhaps over several events), your immune system produces a quantity of antibodies that are capable of recognizing the melanotan II peptide. These antibodies attach to the surfaces of Mast cells in the tissue and Basophils in the bloodstream. When next they encounter the specific foreign substance to which they were designed to detect, they release powerful chemicals such as histamine and heparin into the bloodstream. And it is this release of chemicals which causes the side-effects of the drug.

The degree to which the side-effects occur is directly proportional to how much peptide is in the bloodstream at one time. In the extreme case, anaphylactic shock is a possibility. This is a life-threatening condition characterized by swelling of body tissues, including the throat and hands, headache, uncontrollable itching, constriction of the airways and gastrointestinal symptoms such as abdominal pain, cramps, vomiting, and diarrhea, and a sudden drop in blood pressure. Since most of these dangers stem from the release of the amino acid derivative, histamine, by cells of the immune system, it is my suggestion that some form of anti-histamine be used as a preventive for those people who are especially sensitive to taking melanotan II. Just as well, much lower concentrations of the injected drug would also lessen the side-effects. For those taking notes, extrapolation of this principle out to its limits explains why a slow-release formulation of the drug is so invaluable and so necessary.

There are several types of anti-histamine on the market today including Zyrtec, Allegra, Claritin, Clarinex, and Benadryl. But these drugs can be divided into 1st generation and 2nd generation types. Older drugs such as Benadryl are less selective to the Histamine (H1) receptor and thus, generally cause certain side-effects such as drowiness and/or dizziness and dry mouth. In fact, many over-the-counter sleep aids contain the same active ingredients as Benadryl. The newer 2nd generation anti-histamines are far more selective to H1 and have an improved tolerability profile. The anti-histamine thought to work best is Zyrtec and Allegra. Allegra is non-sedating while Zyrtec may cause some drowiness in certain individuals. Claritin and Clarinex are minimally sedative.

In order to achieve the protection afforded by the anti-histamine, you will want to take it about 45-60 minutes before delivery of melanotan II. What you will achieve by doing this is a blocking of the Histamine receptors such that when Histamine is released into the bloodstream due to an allergen response, it has no where to attach and you will thus ward off an allergic reaction.

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[krieltje]

Top info. Ken zat jongens die hieriin doorslaan,en een negerachtig uiterlijk willen creeren.
Ikzelf wordt er altijd doodziek van.

Ik ga dan ook gewoon melanotan 1 gebruiken ipv 2

 

[jacky den bels]

ik ken er ook die een negert willen lijken niet mooi

 

[2hard2die]

Na enige weken met pijn en hartkloppingen van enige uren te hebben rondgelopen die ik in eerste instantie aanschreef aan de stress die ik momenteel in mijn leven heb en of eventueel aan mijn eerdere AAS gebruik, viel het mij op dat de pijn en kortademigheid het hevigst was na mijn dagelijkse MT prikje.
Omdat ik hier vroeger geen last van had en ik dus al meerdere vials heb gebruikt zonder noemenswaardige problemen, duurde het even voordat ik argwaan kreeg...

Ik heb nu dus zelf helaas (na gebruiken van meerdere succesvolle 'kuren' met MTII) last gekregen van hevige allergische reacties, pijn in borststreek, hartkloppingen, moeilijkheden met ademhaling waarschijnlijk door zwellingen)
Dit alles naast de goed aanvaardbare gebruikelijke bijwerkingen zoals lichte misselijkheid en 'flushes'.
De bijwerkingen nemen in hevigheid toe naar mate ik de dosis verhoog, ook al blijf ik binnen de ' aanbevolen marge'.

ik vond de info na wat google werk.
Ik vraag met af of er meer mensen zijn die heftige bijwerkingen ervaren?

Ik ga nu direct stoppen met gebruik van mtII en misschien later nog eens proberen icm anti-histamine, maar voorlopig ben ik geschrokken.... en is het even genoeg.

---------- Toegevoegd om 14:20 ---------- De post hierboven werd geplaatst om 14:14 ----------

which is why first time users usually don't have any adverse reactions. Upon first introduction (or perhaps over several events), your immune system produces a quantity of antibodies that are capable of recognizing the melanotan II peptide. These antibodies attach to the surfaces of Mast cells in the tissue and Basophils in the bloodstream. When next they encounter the specific foreign substance to which they were designed to detect, they release powerful chemicals such as histamine and heparin into the bloodstream. And it is this release of chemicals which causes the side-effects of the drug.

dit is dus met name het probleem... eerst geeft het middel geen sides, omdat het lichaam het middel nog niet herkend en geen anti-stoffen heeft aangemaakt om het middel 'aan te vechten'. Daarom heb ik waarschijnlijk in vorige kuren MTII geen tot weinig last ondervonden.

wanneer het lichaam dus het middel heeft leren herkennen, kan het zijn afweer vuren en kunnen onderstaande sides optreden: !!!

The degree to which the side-effects occur is directly proportional to how much peptide is in the bloodstream at one time. In the extreme case, anaphylactic shock is a possibility. This is a life-threatening condition characterized by swelling of body tissues, including the throat and hands, headache, uncontrollable itching, constriction of the airways and gastrointestinal symptoms such as abdominal pain, cramps, vomiting, and diarrhea, and a sudden drop in blood pressure.