Ik wist idd dat bier (eigenlijk alcohol in het algemeen, dacht ik) oestrogeen bevat.
Maar is dat niet allemaal relatief? I mean, ga ik verschil merken in gains als ik plots rode wijn begin te zuipen ipv bier?
hopeine is op dit moment het sterkst gekende phyto-oestrogeen. Bij langdurig gebruik krijg je dan de typische pseudo-gynotietjes, of zelfs echte gyno.
Bij rode wijn zijn de onderzoeken heel positief, qua gezondheid en vetverlies, maar je moet ze zelf opzoeken, anders gaat het te ver off-topic. Een kleine hint is resveratrol, ook een phyto-oestrogeen, maar dan aan de andere kant van het spectrum. Maar er zitten nog andere stofjes in rode wijn die zeker even interessant zijn.
Suppression of aromatase (estrogen synthetase) by red wine phytochemicals.
Eng ET, Williams D, Mandava U, Kirma N, Tekmal RR, Chen S.
Division of Immunology, Beckman Research Institute of the City of Hope, Duarte, CA 91010, USA.
Estrogen promotes the proliferation of breast cancer cells. Aromatase is the enzyme that converts androgen to estrogen. In tumors, the expression of aromatase is upregulated compared to surrounding non-cancerous tissue. In this study, we found that wine contains phytochemicals that are capable of suppressing aromatase. Red wine was shown to be much more effective than white wine in the suppression of aromatase activity. Whole wine, lyophilized wine, and heat-treated extracts were examined for aromatase inhibition in a human placenta microsomal assay. C18 Sep-Pak cartridge (Waters Co.) separation of red wine extracts under an increasing acetonitrile (ACN) gradient found that the most active components were in the 20% ACN fraction, in that they inhibited the wild-type human placenta aromatase, wild-type porcine placenta and blastocyst aromatase in a dose-dependent fashion. The 20% ACN active fraction was heat stable and inhibited aromatase in a non-competitive manner. The aromatase-inhibitory action of red wine extracts was also examined with a transgenic mouse model in which aromatase is over-expressed in the mammary tissues. It was found that the intake of the 20% ACN fraction by gavage completely abrogated aromatase-induced hyperplasia and other changes in the mammary tissue. This is the first report demonstrating that wine, especially red wine, contains phytochemicals that can inhibit aromatase.
Of het een merkbaar effect geen, ik vind van wel, en drink nog amper bier.