dnp (dinitrophenol) ik ben benieuwd
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hough it has many uses, 2,4-dinitrophenol is most notorious as a dangerous yet effective weight loss agent and fat burner in the hardcore underground bodybuilding supplement industry.
2,4-Dinitrophenol, more commonly known as DNP, is a solid yellow crystaline that has a sweet, musty odor. It is a manufactured chemical that does not occur naturally in the environment. Caswell #392, Solfo Black, Nitro Cleenup,1 Hydroxy-2,4-dinitrophenol, Nitrophen, Aldifen, and Chemox are some of its aliases.
2,4-Dinitrophenol DNP In The World Of Bodybuilding
Originally used as an ignitor for TNT as well as a pesticide, researchers at Stanford University discovered that DNP causes weight loss in 1933. The late pioneer bodybuilding Dan Duchaine wrote about DNP for fat reducing weight loss and DNP has been used in the hardcore bodybuilding underground for fat and weight loss for decades.
Compared to other thermogenic, fat reducing, and weight loss agents such as the epederine/caffeine/aspirin (ECA) stack would boost the user's metabolism 3% or the Clenbuterol/Cytomel T-3 stack which would boost metabolism 5-10%, DNP was seen to raise metabolism up to a relatively controlled 50% making DNP a seemingly miracle supplement. While clen/t-3, ECA, and others significantly raised the body's temperature, DNP raised internal temperature 2-4 degrees F.
The main problem with DNP is its severe side effects. Exercise during a DNP cycle should be kept to light workouts. DNP has not been seen to cause cancer, but death is a posibility if DNP raises the user's body temperature too high as there is not limit to how hot DNP can make the user's body. The lethal dose of DNP is only 4 times the dose that is effective in losing weight and fat loss.
DNP is not an appetite suppressant, so a user will be hungry, and DNP users will especially crave carbohydrates due to glucose inefficiency. Some users may be allergic, and less than 1% of women who used DNP in the 1930's for fat reducing and weight loss developed cataracts which led to the 1938 FDA 2,4-dinitrophenol DNP ban as a weight loss drug.
DNP since has been used off and on with scrutiny from within and outside the bodybuilding industry. Protesters of DNP note that DNP is not a forgiving chemical. Understanding what the effects, risks, and limitations of the substance are before trying to acquire and use DNP promote their hopes to deter potential DNP users, but the effectiveness of DNP to help with fat reduction and ultimately weight loss is hard to deny. A danger is the fact that DNP has a cumulative effect with a 36-hour half-life. DNP takes up to 48 hours to flush from a user's system. Many bodybuilders adapt the "more is better" theory to their use of DNP severely increasing their risk of harmful side effects and possibly death.
Weight Loss with DNP - Scientifically Speaking
DNP accomplishes the astounding boost in metabolic rate via inhibition of the F0F1 ATP synthase molecule, located in the inner wall of each mitochondrion. While the electron transport chain still functions to pump hydrogen ions into the inter-membrane space, the coupling of the proton gradient to ATP production is rendered impossible by DNP. As a result, ATP production is dramatically reduced, and the energy is instead thrown off as heat. This results in an astounding production of heat; when using dinitrophenol, the athlete will radiate so much heat that it is uncomfortable to be within any proximity of them. Luckily, this heat does not fully contribute to body temperature increases, and is instead thrown off from the entire body surface, particularly the head. As a result, adequate doses of DNP will usually only elevate body temperature by about 1-1.5?C. This is a good thing for your central nervous system and other delicate tissues. If the heat produced by ATP contributed in a more direct matter to body temperature, effective doses for fat loss would cause body temperature increase. Nonetheless, overheating is a very real danger.
Under these conditions, much of the food that we eat could not be used for ATP synthesis and we lose weight. However, too much inhibitor and we could make too little ATP for life. The difference between weight loss and death is only a small concentration change in dinitrophenol, making the drug dangerous. Simply put, this means that while eating your normal diet, you will have somewhere between 20% and 40% reduction of calories.
Risks of using 2,4-Dinitrophenol DNP for Weight Loss
Hearing all of these wonderful things probably has you wondering what the side effects and risks are. They are quite formidable and contribute to making DNP one of the most intolerable (though effective) drugs used in bodybuilding.
CONSUMING DNP FOR WEIGHT LOSS PURPOSES IS NOT RECOMMENDED WHATSOEVER, but if you are exposed to it, you suffer any of these side effects, and they are extremely bothersome, it is the recommendation to cease contact immediately and see your physician as soon as possible. Do not attempt to continue the exposure at that point.
Safe and Effective DNP Dosage...
...at least as safe as it gets when using DNP for weight loss. Dosing is highly individualized and most generalizations tend to collapse quite quickly. As a result, none will be attempted. Start on the low end of the scale and see how you react. It is not recommended to take more than 300mg at any one time.
Getting the right dosage of DNP is rather easy to do although the importance of proper dosage cannot be overstated. It is far better for one to err on the side of too little rather than too much, certainly in the case of the novice who does not know if they are allergic to the substance.
As stated before, the commonly used dosage by bodybuilders and other reasonably lean persons is 4-6mg/kg of bodyweight. This would mean that a 100-kilogram bodybuilder would use anywhere from 400-600mg per day. Experienced users commonly are found using up to 800mg/day relatively safely, and beginners sometimes find that they enjoy 3-5 pounds of fat loss per week with as little as 200mg/day.
So, a person weighing 200 lbs would weigh about 91 kg. So 4mgs per kg of body weight would be the equivalent of 364 mgs of DNP per day. Since DNP comes in 200 mg capsules, the user would take one cap twice daily to stay within range. The lethal dose is a mere 32mg/kg...only 4 times the max effective dose of 800mg/day. The addage "more is better" does not ring true in this case. Heed the warning!
DNP should be taken in 8 to 12-day cycles to avoid liver and kidney damage and to allow your muscles to recover. Bodybuilders typically look their best 48 to 96 hours after cessation of usage. A 10-day cycle of 400mg per day (200mg twice daily) would be a typical effective dose for a 225lb man. This allows for a total of two weeks from start to finish with a 4-day recovery period. Positive results have been seen with a lower dose, but conversely, better results have been achieved safely with a higher dose. Positive results have been seen in users taking 200mg to 800mg per day. Keep the formula of 4-6mg/kg of body weight in mind.
Since DNP has this inhibiting effect, glycolosis is inhibited as well, causing a diabetic effect due to the conversion of glucose without insulin, so you may have heard that people take insulin with DNP. This will counter act the symptoms of lethargy and lack of energy due to DNP's use. Other supplementation is also suggested to limit side effects as stated later in this column.
Timetable of Effects and Symptoms of a DNP Cycle
Day 1 -None; possibly elevated carbohydrate cravings and/or temperature elevation.
Day 2 - T4-T3 conversion has begun to decrease; lethargy possible. Temperature should be elevated, and radiation of heat is noticeable.
Days 3-5 - Body temperature is elevated, with all the effects that one expects from DNP use. In addition, water retention usually becomes manifest here.
Days 6-10 - Definite water retention, along with other symptoms of use; user most likely feels fatter due to having "flatter" muscles (mainly the result of glycogen depletion) and holding water. Final DNP dose taken in the evening of Day 10.
Days 11-12 - DNP is clearing the system slowly. All symptoms are still present.
Days 13-14 - Water should be gone by now, or getting there. Mild diuretics will expedite this. The user will probably notice perceived greater cardiovascular and muscular endurance.
96 Hours After Final Dose - This is when someone tends to look their best. Their glycogen stores are usually compensated at this point and the retained water should be gone.
2,4-Dinitrophenol, more commonly known as DNP, is a solid yellow crystaline that has a sweet, musty odor. It is a manufactured chemical that does not occur naturally in the environment. Caswell #392, Solfo Black, Nitro Cleenup,1 Hydroxy-2,4-dinitrophenol, Nitrophen, Aldifen, and Chemox are some of its aliases.
2,4-Dinitrophenol DNP In The World Of Bodybuilding
Originally used as an ignitor for TNT as well as a pesticide, researchers at Stanford University discovered that DNP causes weight loss in 1933. The late pioneer bodybuilding Dan Duchaine wrote about DNP for fat reducing weight loss and DNP has been used in the hardcore bodybuilding underground for fat and weight loss for decades.
Compared to other thermogenic, fat reducing, and weight loss agents such as the epederine/caffeine/aspirin (ECA) stack would boost the user's metabolism 3% or the Clenbuterol/Cytomel T-3 stack which would boost metabolism 5-10%, DNP was seen to raise metabolism up to a relatively controlled 50% making DNP a seemingly miracle supplement. While clen/t-3, ECA, and others significantly raised the body's temperature, DNP raised internal temperature 2-4 degrees F.
The main problem with DNP is its severe side effects. Exercise during a DNP cycle should be kept to light workouts. DNP has not been seen to cause cancer, but death is a posibility if DNP raises the user's body temperature too high as there is not limit to how hot DNP can make the user's body. The lethal dose of DNP is only 4 times the dose that is effective in losing weight and fat loss.
DNP is not an appetite suppressant, so a user will be hungry, and DNP users will especially crave carbohydrates due to glucose inefficiency. Some users may be allergic, and less than 1% of women who used DNP in the 1930's for fat reducing and weight loss developed cataracts which led to the 1938 FDA 2,4-dinitrophenol DNP ban as a weight loss drug.
DNP since has been used off and on with scrutiny from within and outside the bodybuilding industry. Protesters of DNP note that DNP is not a forgiving chemical. Understanding what the effects, risks, and limitations of the substance are before trying to acquire and use DNP promote their hopes to deter potential DNP users, but the effectiveness of DNP to help with fat reduction and ultimately weight loss is hard to deny. A danger is the fact that DNP has a cumulative effect with a 36-hour half-life. DNP takes up to 48 hours to flush from a user's system. Many bodybuilders adapt the "more is better" theory to their use of DNP severely increasing their risk of harmful side effects and possibly death.
Weight Loss with DNP - Scientifically Speaking
DNP accomplishes the astounding boost in metabolic rate via inhibition of the F0F1 ATP synthase molecule, located in the inner wall of each mitochondrion. While the electron transport chain still functions to pump hydrogen ions into the inter-membrane space, the coupling of the proton gradient to ATP production is rendered impossible by DNP. As a result, ATP production is dramatically reduced, and the energy is instead thrown off as heat. This results in an astounding production of heat; when using dinitrophenol, the athlete will radiate so much heat that it is uncomfortable to be within any proximity of them. Luckily, this heat does not fully contribute to body temperature increases, and is instead thrown off from the entire body surface, particularly the head. As a result, adequate doses of DNP will usually only elevate body temperature by about 1-1.5?C. This is a good thing for your central nervous system and other delicate tissues. If the heat produced by ATP contributed in a more direct matter to body temperature, effective doses for fat loss would cause body temperature increase. Nonetheless, overheating is a very real danger.
Under these conditions, much of the food that we eat could not be used for ATP synthesis and we lose weight. However, too much inhibitor and we could make too little ATP for life. The difference between weight loss and death is only a small concentration change in dinitrophenol, making the drug dangerous. Simply put, this means that while eating your normal diet, you will have somewhere between 20% and 40% reduction of calories.
Risks of using 2,4-Dinitrophenol DNP for Weight Loss
Hearing all of these wonderful things probably has you wondering what the side effects and risks are. They are quite formidable and contribute to making DNP one of the most intolerable (though effective) drugs used in bodybuilding.
CONSUMING DNP FOR WEIGHT LOSS PURPOSES IS NOT RECOMMENDED WHATSOEVER, but if you are exposed to it, you suffer any of these side effects, and they are extremely bothersome, it is the recommendation to cease contact immediately and see your physician as soon as possible. Do not attempt to continue the exposure at that point.
Safe and Effective DNP Dosage...
...at least as safe as it gets when using DNP for weight loss. Dosing is highly individualized and most generalizations tend to collapse quite quickly. As a result, none will be attempted. Start on the low end of the scale and see how you react. It is not recommended to take more than 300mg at any one time.
Getting the right dosage of DNP is rather easy to do although the importance of proper dosage cannot be overstated. It is far better for one to err on the side of too little rather than too much, certainly in the case of the novice who does not know if they are allergic to the substance.
As stated before, the commonly used dosage by bodybuilders and other reasonably lean persons is 4-6mg/kg of bodyweight. This would mean that a 100-kilogram bodybuilder would use anywhere from 400-600mg per day. Experienced users commonly are found using up to 800mg/day relatively safely, and beginners sometimes find that they enjoy 3-5 pounds of fat loss per week with as little as 200mg/day.
So, a person weighing 200 lbs would weigh about 91 kg. So 4mgs per kg of body weight would be the equivalent of 364 mgs of DNP per day. Since DNP comes in 200 mg capsules, the user would take one cap twice daily to stay within range. The lethal dose is a mere 32mg/kg...only 4 times the max effective dose of 800mg/day. The addage "more is better" does not ring true in this case. Heed the warning!
DNP should be taken in 8 to 12-day cycles to avoid liver and kidney damage and to allow your muscles to recover. Bodybuilders typically look their best 48 to 96 hours after cessation of usage. A 10-day cycle of 400mg per day (200mg twice daily) would be a typical effective dose for a 225lb man. This allows for a total of two weeks from start to finish with a 4-day recovery period. Positive results have been seen with a lower dose, but conversely, better results have been achieved safely with a higher dose. Positive results have been seen in users taking 200mg to 800mg per day. Keep the formula of 4-6mg/kg of body weight in mind.
Since DNP has this inhibiting effect, glycolosis is inhibited as well, causing a diabetic effect due to the conversion of glucose without insulin, so you may have heard that people take insulin with DNP. This will counter act the symptoms of lethargy and lack of energy due to DNP's use. Other supplementation is also suggested to limit side effects as stated later in this column.
Timetable of Effects and Symptoms of a DNP Cycle
Day 1 -None; possibly elevated carbohydrate cravings and/or temperature elevation.
Day 2 - T4-T3 conversion has begun to decrease; lethargy possible. Temperature should be elevated, and radiation of heat is noticeable.
Days 3-5 - Body temperature is elevated, with all the effects that one expects from DNP use. In addition, water retention usually becomes manifest here.
Days 6-10 - Definite water retention, along with other symptoms of use; user most likely feels fatter due to having "flatter" muscles (mainly the result of glycogen depletion) and holding water. Final DNP dose taken in the evening of Day 10.
Days 11-12 - DNP is clearing the system slowly. All symptoms are still present.
Days 13-14 - Water should be gone by now, or getting there. Mild diuretics will expedite this. The user will probably notice perceived greater cardiovascular and muscular endurance.
96 Hours After Final Dose - This is when someone tends to look their best. Their glycogen stores are usually compensated at this point and the retained water should be gone.
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rusher
Freaky Bodybuilder
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crystal versie is wel cleaner maar ook velen malen slapper..grote kans dat ie die heeft...ik nam altijd eerst 1000mg dan 800mg en overige dagen 400mg..duurt anders echt heel lang voordat je er wat pas van merkt..
sides...naast het zweten. speirverlies en krachtverlies, gaan je ogen ook heel erg achteruit...search maar eens op cataract + dnp...ik nam daar ook shit voor maar alsnog zijn mn ogen erg achteruit zijn gegaan
owja heel leuke bijwerking vergeten..je sperma wordt geel..fel geel zelfs...ffies schrikken in begin
als je ervaring met slin hebt dan is het goedje wel stuk interessanten...dnp+slin wordt wel eens poor mans igf genoemd..maar ongetwijfld ook wel de meest dodelijke combi die er is...
resultaten zullen alleen goed zijn als je je honger kan beheersen..en dat is echt niet neits..je snakt gewoon naar carbs..vandaar de sibutramine die erbij zit...als je dieet ****ed up is dan zal je eerder vetter erdoor worden dan vet verliezen..
tWack
Advanced Bodybuilder
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rusher
Freaky Bodybuilder
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als ik dit zo lees zijn er genoeg redenen om het idd niet te doen!
omfg
- Lid sinds
- 23 dec 2007
- Berichten
- 4.825
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- 412
- Lengte
- 1m82
- Massa
- 114kg
- Vetpercentage
- 8%
Denk dat je het verkeerd begrijpt. Het werkt zeker wel, maar de voordelen wegen niet op tegen de extreme nadelen volgens hem.
Heb je wel eens T3, Clen of zelfs de combi T3+Clen gebruikt? Ik neem aan van wel als je nu naar de DNP grijpt. Ik zal mn handen er niet aan branden, met T3 en Clen kan ik al knetterdroog en hard komen te staan, zonder spierverlies en minimale bijwerkingen.
Zit je nu echt tegen een plateau aan dat je niet meer goed droger wordt? Want met 16% kan je nog met zat andere middelen en voeding een stuk droger komen te staan kerel.
lorso
Competitive Bodybuilder
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Ik zal je al die typfouten niet kwalijk nemen, nu ik weet dat je wss zo scheel als een aap bent
Een Braille toetsenbord niks voor je
j/K
roberto24
Freaky Bodybuilder
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- 17 apr 2006
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- 5.812
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ik heb al clen en t3 gebruikt en werkt heel goed maar gaat weer zoveel tijd in zitten en ik heb begin september alweer een kuurtje klaarstaan en wil me dan echt op massa concentreren eerste 8 weken en de rest met clen en t3
week 1-8 750 sust
week 1-8 600 deca
week 1-8 400 tren
week 8-14 400 test prop
week 8-14 400 tren ace
week 8-14 masteron
week 8-14 t3 clen op en af bouwen ik hoop als ik klaar ben 104 -108 te wegen met 8-11% met 176 als je iets aan te merken heb of suggesties zou ik het graag horen sta alijd open voor nieuwe ideeen
week 1-8 750 sust
week 1-8 600 deca
week 1-8 400 tren
week 8-14 400 test prop
week 8-14 400 tren ace
week 8-14 masteron
week 8-14 t3 clen op en af bouwen ik hoop als ik klaar ben 104 -108 te wegen met 8-11% met 176 als je iets aan te merken heb of suggesties zou ik het graag horen sta alijd open voor nieuwe ideeen
- Lid sinds
- 28 feb 2007
- Berichten
- 4.041
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- 270
- Lengte
- 1m74
- Massa
- 103kg
- Vetpercentage
- 20%
Ja Cok, voor jou gaat het beginnen! Jij bent mijn persoonlijke proefkonijn Eens kijken wat er voor mij inzit als het bij jou goed gaat. En als je niet de mogelijkheid hebt om te laten weten hier hoe het gaat, dan kan ik ook je vorderingen posten, heb je dan toch wel elke 2 dagen aan de telefoon. Mazzel maatje, tot vanavond misschien enneee... Ik hoop dat ik je toch wel weer zie na die 2/3 weken 
Niet stiekum doodgaan hè!!
Eens kijken wat er voor mij inzit als het bij jou goed gaat. En als je niet de mogelijkheid hebt om te laten weten hier hoe het gaat, dan kan ik ook je vorderingen posten, heb je dan toch wel elke 2 dagen aan de telefoon. Mazzel maatje, tot vanavond misschien enneee... Ik hoop dat ik je toch wel weer zie na die 2/3 weken Niet stiekum doodgaan hè!! 
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- Lid sinds
- 28 feb 2007
- Berichten
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- 270
- Lengte
- 1m74
- Massa
- 103kg
- Vetpercentage
- 20%
Succes ermee Cok
En Animal, doe lief!
Doe ik toch
Hij mag NIET doodgaan en hij MOET weer terugkomen van de camping Anders moet jij me maar tot een beest maken (nee niet alleen in bed )
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Doe ik toch
Haha, ik laat trainen maar aan Cok over, neem ik dat ander gedeelte wel voor mijn rekening
Trouwens, binnenkort uit op dvd: Becoming an Animal 2.0
Starring Animallegs & Cok
gazearek
Advanced Bodybuilder
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- 13 sep 2006
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