Info over Accutane en AAS

[Grote spuit]

Nee, is niet bij de apotheek verkrijgbaar en ja, ik gebruik het zelf ook.

De creme moet 1 x daags dun aangebracht worden op de aangetaste plekken. Hiet moet je wel tijdig mee beginnen, aangezien het, net als bij accutane tabs, ong. 3 weken duurt voordat het zichtbaar begint te werken.
Ik smeer het heel dun op mijn nek, schouders en gezicht 1 x per dag, direct vanaf het begin van de kuur.

Ik ondervind er zelf echt totaal geen bijwerking van, een maat van me krijgt een wat gloeiend gevoel op de plek waar hij het opsmeert en het wordt dan wat rood. Dit is echter normaal volgens de bijsluiter en hoort bij het genezingsproces. Volgens hem is het goed te verdragen.

Dat gloeien verdwijnt vanzelf na een week of wat bij hem, evenals de pukkels bij ons beiden :-)

 

[Nigger]

Dat klinkt goed. Maar werkt die zalf nu evengoed als de pillen van roaccutane?

 

[Grote spuit]

Ja, het werkt even goed, maar heeft minder bijwerkingen dan accutane tabs. Dat wil niet zeggen dat er geen bijwerkingen zijn.

De bijwerkingen van de accutane tabs zijn:

Frequency:

Chapped lips 90%
Dry skin and itching 80% - the use of daily alpha hydroxacids will help prevent this side effect.
Dryness of nose, mild nosebleed 80%
Irritation of the eyelids and eyes 40% - Vitamin E 400 IU each day may lessen this side effect.
Joint and muscle pains 15%
Temporary hair thinning 10%
Rash 7%
Intestinal symptoms 5%
Urinary symptoms 5%
Headache 5%
Increased sensitivity to sunburn 5% - the use of daily sunscreen will help prevent this side effect.
Decreased night vision <1%
Depression, thoughts of suicide <1%
Isotretinoin may increase the level of blood fats, sometimes to risky levels. Occasionally it may affect the liver. That's why regular blood tests are necessary when you are taking isotretinoin; these tests must be done when you have fasted for 12 hours (no breakfast), so that the blood fat determinations are reliable. A baseline blood chemistry test is established before patients start isotretinoin.

The most damaging side effect of isotretinoin capsules is serious birth defects if taken during pregnancy.



De creme mag wel tijdens de zwangerschap gebruikt worden, omdat er minder dan 10% van de tretinoin in de bloedbaan terechtkomt. Dit betekent daarom ook veel minder bijwerkingen.
De mogelijke bijwerkingen van de creme zijn:

Branderig gevoel en roodheid op de behandelde plek, huidpigmentatie, huidschilfering, gevoelig voor zonlicht.

Een heel verschil t.o.v. de tabs dus !!
De bijwerkingen zoals branderig gevoel en roodheid verdwijnen naarmate de behandeling voorduurt, meestal na een week of 2-3 en zijn goed te verdragen. De creme wordt 1 x per dag aangebracht, als de bijwerkingen niet goed bevallen kan tot 1 x per 2 dagen worden overgegaan.

Meer gebruiken dan 1 x per dag lijdt niet tot een beter resultaat, wel tot meer mogelijke bijwerkingen.

Net als bij de tabs moet het minstens 3 maanden gebruikt worden voor maximaal resultaat, de eerste verbeteringen zijn net als bij de tabs na 3-4 weken zichtbaar.

 

[Grote spuit]

Bijsluiter

AIROL

Active Ingredients: Tretinoin (Retinoic acid, Vitamin A acid)

Manufacturer: Pierre Fabre


What Is It Used For?

Airol is used in the treatment of acne. It reduces the formation of pimples and promotes quick healing of pimples that do develop. It even helps prevent new breakouts. Secondly it is used in treating the visible signs of aging and can diminish the lines on the face, helps fading age spots and it can reduce stretchmarks. The third use of topical tretinoin is to help enhance the effects on minoxidil for the treatment of alopecia or hair loss.

How Is It Used?

Apply a thin layer of Airol to affected area at bedtime. Wash hands immediately after use. Using this medication more frequently or in excessive amounts does not improve the results, but may increase side effects. Avoid applying near the eyes, mouth, or open cuts since this medication can irritate sensitive skin. Acne may appear to worsen when the medication is first used; continue therapy. It may take three to six weeks before the full benefits of this medication are seen. Tretinoin is for external use only, do not take by mouth.
Topical tretinoin appears to increase the beneficial effects of minoxidil, and it is thought that this is due to increased absorption of minoxidil through alteration of the stratum cornum barrier. One study showed a triple absorption with 0.05 tretinoin as compared with a control vehicle.

Contact your pediatrician or health care professional regarding the use of this medicine in children. Special care may be needed.


Are There Possible Side Effects?

Immediately after applying, the skin may feel warm or mild stinging or redness may occur. Some peeling of the skin may occur. These effects should subside as your skin adjusts to the medication. This medicine may also increase sun sensitivity.

Side effects that usually do not require medical attention : increased sensitivity to the sun, mild stinging, red, inflamed, and irritated skin, the skin may peel after a few days.


Is It Safe?

This medication can increase sensitivity to sunlight, wind and cold. Avoid prolonged exposure to the sun and sunlamps. Wear protective clothing and use an effective sunscreen. This medication should be used during pregnancy only if clearly needed.
Use mild soap when washing your face. Do not wash face excessively. Abrasive soaps, cleansers, medicated creams or lotions can increase skin irritation. Consult your doctor or pharmacist about their use. Use other acne preparations with caution while using this medication.


What About Interactions With Other Drugs?

Inform your doctor about all the medicines you take with and without a prescription.
They need to know if you have any of these conditions: eczema, sunburn, an unusual or allergic reaction to tretinoin, vitamin A, other medicines, foods, dyes, or preservatives, pregnant or trying to get pregnant, breast-feeding.


What If I Miss A Dose?

If you miss a dose, use it as soon as remembered; do not use if it is almost time for the next dose, instead, skip the missed dose and resume your usual dosing schedule. Do not "double-up" the dose to catch up. Too much tretinoin can cause skin damage.

How Should It Be Stored?

Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at a controlled room temperature, 15°C to 30°C (59°F to 86°F) and away from excess heat and moisture (not in the bathroom). Throw away any medication that is outdated or no longer needed.

Anything Else I Should Know?

Cosmetics may be used, but clean skin thoroughly before applying the medication.
Your acne may get worse during the first treatment period and should then start to improve. It may take 2 to 12 weeks before you see the full beneficial effect.

Do not wash your face more than 2 or 3 times a day, unless told to by your prescriber or health care professional. Do not use the following products on the same areas that you are treating with tretinoin, unless otherwise directed by your prescriber or health care professional: medicated cosmetics, cosmetics that dry the skin (especially products that contain alcohol), abrasive soaps or cleaners, and any other acne preparation or skin treatment. If you use these products in combination with tretinoin they can cause severe skin irritation. You can use non-medicated cosmetics (unless your prescriber or health care professional tells you not to); wash the skin well before applying tretinoin.

Tretinoin can increase sensitivity of the skin to sun or UV light. Keep out of the sun, or wear protective clothing outdoors and use a sunscreen (SPF 15 or higher). Do not use sun lamps or sun tanning beds or booths.

Tretinoin products can catch fire. Keep away from lighted matches, cigarettes and other naked flames.

Do not get tretinoin in the eyes, inside the nose, on wounds, or any other sensitive areas of skin.