Jaytjuh
Freaky Bodybuilder
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- 8 jul 2009
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deca werkt op de progesteron receptoren in je ogen
Tattoo zetten tijdens kuur ?
- Topic starter BRIAN DE VE
- Startdatum
- Recente activiteit Recente activiteit:
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- kuur
deca werkt op de progesteron receptoren in je ogen
Stimulation of collagen synthesis by the anabolic steroid stanozolol.
Falanga V, Greenberg AS, Zhou L, Ochoa SM, Roberts AB, Falabella A, Yamaguchi Y.
Source
University of Miami School of Medicine, Department of Dermatology, Miami Veterans Affairs Medical Center, Florida, USA.
Abstract
There is evidence that anabolic steroids, which are derived from testosterone and have markedly less androgenic activity, promote tissue growth and enhance tissue repair; however, the mechanisms involved in their anabolic activities remain unclear. In this report, we measured the effect of the anabolic steroid stanozolol on cell replication and collagen synthesis in cultures of adult human dermal fibroblasts. Stanozolol (0.625-5 microg per ml) had no effect on fibroblast replication and cell viability (p = 0.764) but enhanced collagen synthesis (p < 0.01) in a dose-dependent manner (r = 0.907). Stanozolol also increased (by 2-fold) the mRNA levels of alpha1 (I) and alpha1 (III) procollagen and, to a similar extent, upregulated transforming growth factor-beta1 (TGF-beta1) mRNA and peptide levels (p < 0.001). There was no stimulation of collagen synthesis by testosterone. The stimulatory effects of stanozolol on collagen synthesis were blocked by a TGF-beta1 anti-sense oligonucleotide, by antibodies to TGF-beta, and in dermal fibroblast cultures derived from TGF-beta1 knockout mice. We conclude that collagen synthesis is increased by the anabolic steroid stanozolol and that, for the most part, this effect is due to TGF-beta1. These findings point to a novel mechanism of action of anabolic steroids.
Falanga V, Greenberg AS, Zhou L, Ochoa SM, Roberts AB, Falabella A, Yamaguchi Y.
Source
University of Miami School of Medicine, Department of Dermatology, Miami Veterans Affairs Medical Center, Florida, USA.
Abstract
There is evidence that anabolic steroids, which are derived from testosterone and have markedly less androgenic activity, promote tissue growth and enhance tissue repair; however, the mechanisms involved in their anabolic activities remain unclear. In this report, we measured the effect of the anabolic steroid stanozolol on cell replication and collagen synthesis in cultures of adult human dermal fibroblasts. Stanozolol (0.625-5 microg per ml) had no effect on fibroblast replication and cell viability (p = 0.764) but enhanced collagen synthesis (p < 0.01) in a dose-dependent manner (r = 0.907). Stanozolol also increased (by 2-fold) the mRNA levels of alpha1 (I) and alpha1 (III) procollagen and, to a similar extent, upregulated transforming growth factor-beta1 (TGF-beta1) mRNA and peptide levels (p < 0.001). There was no stimulation of collagen synthesis by testosterone. The stimulatory effects of stanozolol on collagen synthesis were blocked by a TGF-beta1 anti-sense oligonucleotide, by antibodies to TGF-beta, and in dermal fibroblast cultures derived from TGF-beta1 knockout mice. We conclude that collagen synthesis is increased by the anabolic steroid stanozolol and that, for the most part, this effect is due to TGF-beta1. These findings point to a novel mechanism of action of anabolic steroids.
Ernstige brandwondenpatiënten word ook deca voorgeschreven ivm genezing
is dit ivm genezing van de huid of algemene aansterking, zie mn eerdere post
- Lid sinds
- 19 jan 2007
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- 1m75
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ik denk het niet, meeste patienten hebben schade aan spierweefsel en immuumsysteem, daar kun je deca voor gebruiken. huidtechnisch weinig voordeel mee te behalen denk ik
- Lid sinds
- 19 jan 2007
- Berichten
- 2.823
- Waardering
- 1.017
- Lengte
- 1m75
- Massa
- 101kg
- Vetpercentage
- 10%
- Lid sinds
- 23 apr 2007
- Berichten
- 2.197
- Waardering
- 60
- Lid sinds
- 15 apr 2006
- Berichten
- 2.216
- Waardering
- 51
- Lengte
- 1m98
- Massa
- 110kg
- Vetpercentage
- 15%
- Lid sinds
- 19 jan 2007
- Berichten
- 2.823
- Waardering
- 1.017
- Lengte
- 1m75
- Massa
- 101kg
- Vetpercentage
- 10%
Tja je kan ook geluk gehad hebben
Ik zeg ook niet dat het bij iedereen een probleem is hoor, maar ik heb genoeg gasten gezien die kort na het tattooeren zijn gaan trainen, en daarna een blauwe waas rond de tattoo kregen, lijnen die veel dikker werden, etc..
Ik moet er wel bij zeggen dat dit vooral op plekken gebeurt waar veel beweging en spanning opstaat, zoals borst, en onderkant bicep (in de knik tussen bicep en onderarm)
