OxymetholoneFrom Wikipedia, the free encyclopediaJump to: navigation, search This article needs additional citations for verification. Please help improve this article by adding citations to reliable sources. Unsourced material may be challenged and removed. (January 2012)
Oxymetholone
Systematic (IUPAC) name
17β-hydroxy-2-hydroxymethylidene-
17α-methyl-3-androstanone
Clinical data
AHFS/Drugs.com Consumer Drug Information
Pregnancy cat. X
Legal status Schedule III
(US)
Routes Oral
Pharmacokinetic data
Bioavailability 95%
Metabolism Hepatic
Half-life 8-9 hours
Excretion Urinary:95%
Identifiers
CAS number 434-07-1 N
ATC code A14AA05
PubChem CID 5281034
ChemSpider 4444502 Y
UNII L76T0ZCA8K Y
KEGG D00490 Y
ChEMBL CHEMBL1200585 N
Chemical data
Formula C21H32O3
Mol. mass 332.48 g/mol
SMILES eMolecules & PubChem
InChI[show]InChI=1S/C21H32O3/c1-19-11-13(12-22)18(23)10-14(19)4-5-15-16(19)6-8-20(2)17(15)7-9-21(20,3)24/h12,14-17,22,24H,4-11H2,1-3H3/b13-12-/t14-,15+,16-,17-,19-,20-,21-/m0/s1 Y
Key:ICMWWNHDUZJFDW-DHODBPELSA-N Y
N (what is this?) (verify)
Oxymetholone, marketed as Anadrol, is a synthetic anabolic steroid developed in 1960 by Zoltan 'Anadrol Z' F.[citation needed] Its primary clinical applications include treatment of osteoporosis and anaemia, as well as stimulating muscle growth in malnourished or underdeveloped patients. The drug was approved for human use by the FDA. Later, non-steroidal drugs such as epoetin alfa were developed and proven to be more effective as a treatment for anaemia and osteoporosis without the side effects of oxymetholone. The drug remained available despite this and eventually found a new use in treating HIV wasting syndrome. Presented most commonly as a 50 mg tablet, oxymetholone is one of the strongest androgenic steroids available.[1] Similarly, it also poses the greatest risk of side effects of any steroid. Despite very low binding affinity with the androgen receptor, oxymetholone is highly effective in promoting extensive gains in body mass, mostly by greatly improving protein synthesis. For this reason, it is often used by bodybuilders and athletes. Many athletes also use oxymetholone as a method of protection for the joints under heavy loads. Due to the high water retention users experience from this drug, it similarly lubricates the joints and helps protect from injury.[citation needed] Oxymetholone is widely considered by bodybuilders to have the strongest anabolic effect out of all oral steroids available.
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