I recently took a course of letro to try and reduce a gyno lump that had developed after a previous cycle. During the first week I felt pretty rough but after that I felt better mentally and emotionally than I have in a very long time. I quite often have mild feelings of anxiety and depression and all this stopped while I was taking letro. Now that I've stopped the letro those mild issues have returned. I went to the doctor last week for a general check up and I'm in great shape apart from my cholesterol being a little on the low side. If anyone has any ideas as to why letro would have this effect on me I'd like to hear them. I haven't been on a cycle for over a year. And it's not like I don't function just fine now, I just noticed I functioned considerably better mentally while on letro. Any ideas will be much appreciated.