In men, obesity is the single most important factor associated with low testosterone, overriding the effects of age and comorbidities [3]. Obese men have 30 % lower total testosterone (TT) levels compared to lean men [3], and 40 % have levels lower than 12 nmol/L [3], the lower limit reported for healthy young men [4]. This reduction in total testosterone levels is in part due to the obesity-associated lowering in sex hormone binding globulin (SHBG). However, especially with more marked obesity, free testosterone levels are also reduced due to adiposity-associated suppression of the gonadal axis at the hypothalamic level.
Daarbij zijn dikke mannen letterlijk beta males