Dus als je denkt: Ik heb mn macro's binnen, heb nog 600kcal tegoed en neem lekker een pak koek / big mac, dit is wat er dan eigenlijk gebeurt:
Apparent skeletal muscle loss related to dietary trans fatty acids in a mixed group of omnivores and vegetarians
The well-fed free-living adult subjects in this study show evidence of skeletal muscle loss, evaluated from the increased levels of plasma alanine (p < 0.0001) and decreased urinary levels of isoleucine, leucine, lysine, glycine and alanine (all p values <0.005). Plasma fatty acid analysis showed low percentages of cis-linoleic acid associated with high percentages of both trans-linoleic acid and Mead’s acid. Combining the fatty acid findings with the amino acid results in a multiple regression analysis revealed that the low levels of cis-linoleic acid are independently associated with high levels of both trans-linoleic acid (p = 0.049) and Mead’s acid (p = 0.0001) and with low levels of both urinary alanine (p = 0.047) and plasma glycine (p = 0.001). These results suggest an interactive relationship between cis and trans linoleic acid that could easily disrupt prostaglandin control of absorption/utilization of the amino acids from dietary protein intake.
http://www.ergogenics.org/nac.html#dikker
En nog meer:
http://www.ncbi.nlm.nih.gov/pubmed/21228440
Dietary trans-fatty acids and metabolic syndrome
Trans-fatty acids (TFAs), products of partial hydrogenation of vegetable oils, have become more prevalent in our diet since the 1960s, when they replaced animal fats. TFAs also occur naturally in meat and dairy products from ruminants. There is growing evidence that dietary trans-fatty acids may increase the risk of metabolic syndrome. Several studies have demonstrated adverse effects of TFAs on plasma lipids and lipoproteins. In dietary trials, trans-fatty acids have been shown to raise the total cholesterol/HDL cholesterol ratio and Lp(a) levels in blood. Moreover, a high intake of TFAs has been associated with an increased risk of coronary heart disease.
Prospective cohort studies have shown that dietary trans-fatty acids promote abdominal obesity and weight gain. In addition, it appears that TFA consumption may be associated with the development of insulin resistance and type 2 diabetes. The documented adverse health effects of TFAs emphasise the importance of efforts to reduce the content of partially hydrogenated vegetable oils in foods.
Dus ik zou zeggen, denk nog maar 2x na, voordat je je 'resterende kcalls' wilt invullen, na behalen van macro's
